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Article

[Liver cirrhosis patogenetics: polymorphism of glutation S-transferase genes].

Molekuliarnaia biologiia - 1 Jan 2000

Goncharova I A, Rachkovskiĭ M I, Beloborodova E V, Gamal' Abd El'-Aziz Nasar Kh, Puzyrev V P

Abstract excerpt

Association of deletion polymorphism in GSTT1 and GSTM1 genes and polymorphic variant A313G of GSTP1 gene with cirrhosis diseases and 4-year survival rate for the Tomsk region (West Siberia) patients were tested. Homozygous deletion of GSTM1 gene (null genotype) was a protective factor for alcoholic and mixed (HCV, HBV and alcohol) liver cirrhosis development. The patients from the joint group (all etiology...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20608166
DOI: 10.1134/s0026893310030118

Genes

GSTM1
GSTP1
GSTT1

Variants

Provenance

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