Article
Phenotyping drug disposition in oncology.
Cancer treatment reviews - 1 Oct 2012
Opdam Frans L, Gelderblom Hans, Guchelaar Henk-Jan
Abstract excerpt
Efficacy and toxicity of anticancer agents are highly variable between patients and variation in drug disposition is thought to be an important determinant. Genetics, physiology, and environment all are underlying factors contributing to this variation. Phenotyping drug metabolizing enzymes and d...
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