Article
Cancer pharmacogenomics: implications on ethnic diversity and drug response.
Pharmacogenetics and genomics - 1 May 2015
Patel Jai N
Abstract excerpt
The goal of pharmacogenomic research is to discover and validate genetic variants that are predictive of drug response, for eventual implementation into clinical practice. Cancer pharmacogenomics provides the opportunity to analyze two sets of DNA, that of the tumor (somatic) and that of the host (germline). Germline variants are inherited variations and are often associated with the pharmacokinetic behavior of a...
Topics
- Ethnicity
- Genetic Variation
- Genetics, Population
- Humans
- Neoplasms
- Pharmacogenetics
- Polymorphism, Single Nucleotide