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Article

Nuclear accumulation of beta-catenin occurs commonly in the epithelial cells of juvenile polyps.

Pediatric research - 1 Jan 2005

Iwamoto Michiko, Hoffenberg Edward J, Carethers John M, Doctolero Ryan, Tajima Akihiro, Sugano Kentaro, Franklin Wilbur A, Ahnen Dennis J

Abstract excerpt

In the two conditions juvenile polyps (JPs) and juvenile polyposis coli (JPC), colonic polyps may have overlapping histologic and phenotypic appearance, but JPC confers a significant risk for colon adenocarcinoma. Although not thought to contain adenomatous polyposis coli (APC) mutations, the status of beta-catenin and full-length APC protein expression in JPs is not known. We evaluated beta-catenin and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15557107
DOI: 10.1203/01.PDR.0000148062.57051.8F

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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