Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C314T polymorphism in histamine N-methyltransferase gene and susceptibility to duodenal ulcer in Chinese population.

Clinica chimica acta; international journal of clinical chemistry - 1 Mar 2008

Hailong Cao, Cao Haillong, Mei Qiao, Zhang Lei, Xu Jianming

Abstract excerpt

BACKGROUND: Histamine is a regulator of gastric acid secretion, which is involved in the development of duodenal ulcer (DU). Histamine is metabolized by both histamine N-methyltransferase (HNMT) and diamine oxidase, and its local action is terminated primarily by methylation which is catalyzed by HNMT. METHODS: Polymerase chain reaction-restriction fragment length polymorphism assay was used to identify the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Duodenal Ulcer

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 18086566
DOI: 10.1016/j.cca.2007.11.022

Genes

HNMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C314T polymorphism in histamine N-methyltransferase gene and susceptibility to duodenal ulcer in Chinese population.PMID 18086566Read ↗

Single nucleotide polymorphisms and haplotypes of histamine N-methyltransferase in patients with gastric ulcer.Semantic proximity Read ↗

Analysis of the C314T and A595G mutations in histamine N-methyltransferase gene in a Chinese population.Semantic proximity Read ↗

Genotype-phenotype correlation for histamine N-methyltransferase in a Chinese Han population.Semantic proximity Read ↗

Histamine N-methyltransferase and diamine oxidase gene polymorphisms in patients with inflammatory and neoplastic intestinal diseases.Semantic proximity Read ↗

Association between two polymorphisms of histamine-metabolising enzymes and the severity of allergic rhinitis in a group of Mexican children.Semantic proximity Read ↗

Histamine pharmacogenomics.Semantic proximity Read ↗

Association of diamine oxidase and histamine N-methyltransferase polymorphisms with presence of migraine in a group of Mexican mothers of children with allergies.Semantic proximity Read ↗

Severity of ulcerative colitis is associated with a polymorphism at diamine oxidase gene but not at histamine N-methyltransferase gene.Semantic proximity Read ↗

Histamine N-methyltransferase gene polymorphisms in Chinese and their relationship with enzyme activity in erythrocytes.Semantic proximity Read ↗

Histamine-N-methyl transferase polymorphism and risk for migraine.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities.Semantic proximity Read ↗

Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.