The Role of Platelets and von Willebrand Factor in the Procoagulant Phenotype of Inflammatory Bowel Disease.

doi:10.1093/ecco-jcc/jjad198

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Article

The Role of Platelets and von Willebrand Factor in the Procoagulant Phenotype of Inflammatory Bowel Disease.

Journal of Crohn's & colitis - 31 May 2024

Schellenberg Célia, Lagrange Jérémy, Ahmed Muhammad Usman, Arnone Djésia, Campoli Philippe, Louis Huguette, Touly Nina, Caron Bénédicte, Plénat François, Perrin Julien, Lenting Peter J, Regnault Véronique, Lacolley Patrick, Denis Cécile V, Peyrin-Biroulet Laurent

Abstract excerpt

AIMS: Although the risk of thrombosis is well documented for inflammatory bowel disease [IBD] patients, the underlying pathological mechanism seems to be different from other thrombotic conditions. Determining the factors responsible for the increased risk of thrombosis in IBD would help to improve the management of this frequent complication. METHODS: We studied the interplay between platelets, coagulation, and...

Topics

Adult
Animals
Female
Humans
Male
Mice
Middle Aged
Blood Coagulation
Blood Platelets
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Colitis

Disease Models, Animal

Inflammatory Bowel Diseases

Mice, Inbred C57BL

Phenotype

Thrombin

Thrombosis

von Willebrand Factor

Source

Open in PubMed

Identifiers

PMID: 38011752
DOI: 10.1093/ecco-jcc/jjad198

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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