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Article

Transcriptional repression of catalase in mouse skin tumor progression.

Neoplasia (New York, N.Y.) - 1 Jan 2000

Kwei Kevin A, Finch Joanne S, Thompson Eric J, Bowden G Tim

Abstract excerpt

Previous studies in our laboratory have shown that the elevation of reactive oxygen species levels and the repression of the antioxidant enzyme, catalase, played a critical role in the in vitro progression of benign papilloma cells to malignant carcinoma cells. Catalase message, protein levels, and activity levels were found to be downregulated in the malignantly progressed cells. The goal of this study is to...

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Identifiers

PMID: 15548352
DOI: 10.1593/neo.04127
PMCID: PMC1550329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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