Deficiency in catalase activity correlates with the appearance of tumor phenotype in human keratinocytes.

doi:10.1002/ijc.2910450529

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Article

Deficiency in catalase activity correlates with the appearance of tumor phenotype in human keratinocytes.

International journal of cancer - 15 May 1990

Rabilloud T, Asselineau D, Miquel C, Calvayrac R, Darmon M, Vuillaume M

Abstract excerpt

Biopsies isolated from various human stratified epitheliomas and cultures of the associated fibroblasts exhibit a breakdown in catalase activity (70 to 95%). We report here that primary human cultures of keratinocytes and various immortalized keratinocyte cell lines differ from one other in their...

Topics

Acatalasia
Catalase
Cell Line
Cell Transformation, Neoplastic
Cells, Cultured
Humans
Hydrogen Peroxide
Keratinocytes
Kinetics
Phenotype
Tumor Cells, Cultured

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