Article
Deficiency in catalase activity correlates with the appearance of tumor phenotype in human keratinocytes.
International journal of cancer - 15 May 1990
Rabilloud T, Asselineau D, Miquel C, Calvayrac R, Darmon M, Vuillaume M
Abstract excerpt
Biopsies isolated from various human stratified epitheliomas and cultures of the associated fibroblasts exhibit a breakdown in catalase activity (70 to 95%). We report here that primary human cultures of keratinocytes and various immortalized keratinocyte cell lines differ from one other in their catalase activity. Moreover, deficient catalase activity appears to be related to the intensity of tumor phenotype...
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