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Article

Arginase I is constitutively expressed in human granulocytes and participates in fungicidal activity

17 Nov 2004

Abstract excerpt

The balance of arginine metabolism via nitric oxide synthase (NOS) or arginase is an important determinant of the inflammatory response of murine macrophages and dendritic cells. Here we analyzed the expression of the isoform arginase I in human myeloid cells. Using healthy donors and patients with arginase I deficiency, we found that in human leukocytes arginase I is constitutively expressed only in granulocytes...

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Share to Antibiotics Pharmacokinetics and Efficacy
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Share to Nitric Oxide and Endothelin Effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15546957
DOI: 10.1182/blood-2004-07-2521

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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