Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The human arginases and arginase deficiency

1 Jun 1998

Abstract excerpt

Arginase is the final enzyme in the urea cycle. Its deficiency is the least frequently described disorder of this cycle. It results primarily in elevated blood arginine, and less frequently in either persistent or acute elevations in blood ammonia. This appears to be due to a second arginase locus, expressed primarily in the kidney, which can be recruited to compensate, in part, for the deficiency of liver...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Enzymes and Metabolism
Share to Metabolism and Genetic Disorders
Share to Nitric Oxide and Endothelin Effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9686347
DOI: 10.1023/a:1005313809037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The human arginases and arginase deficiencyPMID 9686347Read ↗

Arginase-1 deficiency.Semantic proximity Read ↗

Arginase deficiency manifesting delayed clinical sequelae and induction of a kidney arginase isozymeSemantic proximity Read ↗

Mutations and common variants in the human arginase 1 (ARG1) gene: Impact on patients, diagnostics, and protein structure considerations.Semantic proximity Read ↗

Drosophila arginase is produced from a nonvital gene that contains the elav locus within its third intron.Semantic proximity Read ↗

Case series of arginase 1 deficiency: Expanding the spectrum in hyperargininemia.Semantic proximity Read ↗

Divergent roles of red cell arginase in humans and mice: RBC Arg1 KO mice show preserved systemic l-arginine bioavailability and infarct size in vivoSemantic proximity Read ↗

Molecular basis of hyperargininemia: structure-function consequences of mutations in human liver arginase.Semantic proximity Read ↗

Generation of a mouse model for arginase II deficiency by targeted disruption of the arginase II gene.Semantic proximity Read ↗

Clinical phenotype, biochemical profile, and treatment in 19 patients with arginase 1 deficiency.Semantic proximity Read ↗

Molecular basis of argininemia. Identification of two discrete frame-shift deletions in the liver-type arginase gene.Semantic proximity Read ↗

Clinical Characteristics of Arginase 1 Deficiency: Natural History Insights From International Clinical Trials.Semantic proximity Read ↗

Optimizing therapy for argininosuccinic aciduria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.