Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome.

Molecular cell - 19 Nov 2004

Flory Mark R, Carson Andrew R, Muller Eric G, Aebersold Ruedi

Abstract excerpt

Abnormal centrosomal structures similar to those occurring in human cancers are induced in fission yeast by overexpression of the pericentrin homolog Pcp1p. Analysis of abnormal Pcp1p-containing structures with quantitative mass spectrometry and isotope-coded affinity tags identified a coiled-coil, structural maintenance of chromosomes (SMC) domain protein. This protein, termed Ccq1p (coiled-coil protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Chromosomes, Fungal
Share to Fluorescence Resonance Energy Transfer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Mapping

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Share to Telomere

Share to Telomere-Binding Proteins

Source

Identifiers

PMID: 15546621
DOI: 10.1016/j.molcel.2004.10.027

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An SMC-domain protein in fission yeast links telomeres to the meiotic centrosome.PMID 15546621Read ↗

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase.Semantic proximity Read ↗

Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis.Semantic proximity Read ↗

A pseudo-meiotic centrosomal function of TEX12 in cancerSemantic proximity Read ↗

Fission yeast Pot1-Tpp1 protects telomeres and regulates telomere length.Semantic proximity Read ↗

The telomere protein Taz1 is required to prevent and repair genomic DNA breaks.Semantic proximity Read ↗

Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore.Semantic proximity Read ↗

Msc1 acts through histone H2A.Z to promote chromosome stability in Schizosaccharomyces pombe.Semantic proximity Read ↗

Fission yeast Pcp1 links polo kinase-mediated mitotic entry to gamma-tubulin-dependent spindle formation.Semantic proximity Read ↗

The yeast homolog to mouse Tcp-1 affects microtubule-mediated processes.Semantic proximity Read ↗

Mutations in CTC1, encoding conserved telomere maintenance component 1, cause Coats plus.Semantic proximity Read ↗

The yeast SRM1 protein and human RCC1 protein share analogous functions.Semantic proximity Read ↗

Pathogenic CTC1 mutations cause global genome instabilities under replication stress.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.