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Article

Digital single-nucleotide polymorphism analysis for allelic imbalance.

Methods in molecular medicine - 1 Jan 2005

Chang Hsueh-Wei, Shih Ie-Ming

Abstract excerpt

Digital single-nucleotide polymorphism (SNP) analysis is developed to amplify a single template from a pool of DNA samples, thereby generating the amplicons that are homogeneous in sequence. Different fluorophores are then applied as probes to detect and discriminate different alleles (paternal vs maternal alleles or wild-type vs mutant), which can be readily counted. In this way, digital SNP analysis transforms...

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PMID: 15542903
DOI: 10.1385/1-59259-780-7:137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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