Article
Will admixture mapping work to find disease genes?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Aug 2005
Reich David, Patterson Nick
Abstract excerpt
Admixture mapping is the first experimentally practical method for carrying out a whole-genome association scan, and is thus a promising method for detecting risk factors for common disease. The goal of the community should now be to aggressively test whether the method is useful in practice for localizing disease genes, by carrying out at least three high-powered studies. We also propose a stringent criteria we...
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