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Article

Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity.

The EMBO journal - 24 Nov 2004

Takehana Aya, Yano Tamaki, Mita Shizuka, Kotani Atsushi, Oshima Yoshiteru, Kurata Shoichiro

Abstract excerpt

In innate immunity, pattern recognition molecules recognize cell wall components of microorganisms and activate subsequent immune responses, such as the induction of antimicrobial peptides and melanization in Drosophila. The diaminopimelic acid (DAP)-type peptidoglycan potently activates imd-dependent induction of antibacterial peptides. Peptidoglycan recognition protein (PGRP) family members act as pattern...

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Identifiers

PMID: 15538387
DOI: 10.1038/sj.emboj.7600466
PMCID: PMC533052

Genes

DAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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