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Article

HOXB13 promotes ovarian cancer progression

17 Oct 2007

Abstract excerpt

Deregulated expression of HOXB13 in a subset of estrogen receptor-positive breast cancer patients treated with tamoxifen monotherapy is associated with an aggressive clinical course and poor outcome. Because the ovary is another hormone-responsive organ, we investigated whether HOXB13 plays a role in ovarian cancer progression. We show that HOXB13 is expressed in multiple human ovarian cancer cell lines and...

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PMID: 17942676
DOI: 10.1073/pnas.0707938104

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