Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Allele-dependent similarity between viral and self-peptide presentation by HLA-B27 subtypes.

The Journal of biological chemistry - 28 Jan 2005

Fiorillo Maria Teresa, Rückert Christine, Hülsmeyer Martin, Sorrentino Rosa, Saenger Wolfram, Ziegler Andreas, Uchanska-Ziegler Barbara

Abstract excerpt

Molecular mimicry is discussed as a possible mechanism that may contribute to the development of autoimmune diseases. It could also be involved in the differential association of the human major histocompatibility subtypes HLA-B(*)2705 and HLA-B(*)2709 with ankylosing spondylitis. These two subtypes differ only in residue 116 of the heavy chain (Asp in B(*)2705 and His in B(*)2709), but the reason for the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigen Presentation
Share to Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Autoimmune Diseases

Share to Epstein-Barr Virus Nuclear Antigens

Share to HLA-B27 Antigen

Share to Receptors, Antigen, T-Cell

Share to T-Lymphocytes, Cytotoxic

Share to Viral Matrix Proteins

Source

Identifiers

PMID: 15537660
DOI: 10.1074/jbc.M410807200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Allele-dependent similarity between viral and self-peptide presentation by HLA-B27 subtypes.PMID 15537660Read ↗

Dual, HLA-B27 Subtype-dependent Conformation of a Self-peptideSemantic proximity Read ↗

Conformational Dimorphism of Self-peptides and Molecular Mimicry in a Disease-associated HLA-B27 SubtypeSemantic proximity Read ↗

Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell SelectionSemantic proximity Read ↗

Binding of peptides naturally presented by HLA-B27 to the differentially disease-associated B*2704 and B*2706 subtypes, and to mutants mimicking their polymorphism.Semantic proximity Read ↗

ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-EpitopesSemantic proximity Read ↗

The Peptide Repertoires of HLA-B27 Subtypes Differentially Associated to Spondyloarthropathy (B*2704 and B*2706) Differ by Specific Changes at Three Anchor PositionsSemantic proximity Read ↗

Uncommon P1 Anchor-featured Viral T Cell Epitope Preference within HLA-A*2601 and HLA-A*0101 Individuals.Semantic proximity Read ↗

HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural AlterationsSemantic proximity Read ↗

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides.Semantic proximity Read ↗

Large sharing of T-cell epitopes and natural ligands between HLA-B27 subtypes (B*2702 and B*2705) associated with spondyloarthritis.Semantic proximity Read ↗

High T cell epitope sharing between two HLA-B27 subtypes (B*2705 and B*2709) differentially associated to ankylosing spondylitis.Semantic proximity Read ↗

Molecular mechanism of the susceptibility difference between HLA-B*27:02/04/05 and HLA-B*27:06/09 to ankylosing spondylitis: substitution analysis, MD simulation, QSAR modelling, and in vitro assay.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.