Diet effects on female reproduction in high growth (hg/hg) mice that are deficient in the Socs-2 gene.

doi:10.1051/rnd:2004035

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Diet effects on female reproduction in high growth (hg/hg) mice that are deficient in the Socs-2 gene.

Reproduction, nutrition, development - 1 Jan 2000

Corva Pablo M, Mucci Nicolás C, Evans Kristin, Medrano Juan F

Abstract excerpt

The detrimental effect of larger body size on reproductive performance has been well documented in mouse models of overgrowth, such as Growth Hormone (GH) transgenics. This study describes the reproductive performance of the High Growth (HG) mouse model of overgrowth. The HG mouse model exhibits overgrowth due to a partially recessive autosomal mutation that increases growth rate and mature body size. The HG...

Topics

Animals
Body Composition
DNA-Binding Proteins
Diet
Disease Models, Animal
Female
Genotype
Growth Hormone
Litter Size
Mice
Mice, Inbred C57BL
Mice, Mutant Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Obesity

Random Allocation

Repressor Proteins

Reproduction

Suppressor of Cytokine Signaling Proteins

Trans-Activators

Source

Open in PubMed

Identifiers

PMID: 15535462
DOI: 10.1051/rnd:2004035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diet effects on female reproduction in high growth (hg/hg) mice that are deficient in the Socs-2 gene.PMID 15535462Read ↗

Diet effects on weight gain and body composition in high growth (hg/hg) mice.Semantic proximity Read ↗

Somatotropic Signaling: Trade-Offs Between Growth, Reproductive Development, and LongevitySemantic proximity Read ↗

Somatotropic Axis, Pace of Life and AgingSemantic proximity Read ↗

Impact of Growth Hormone-Related Mutations on Mammalian AgingSemantic proximity Read ↗

Pleiotropic effects of growth hormone signaling in aging.Semantic proximity Read ↗

Lack of Socs2 expression causes the high-growth phenotype in mice.Semantic proximity Read ↗

High-fat and high-sucrose diet impairs female reproduction by altering ovarian transcriptomic and metabolic signaturesSemantic proximity Read ↗

Quantitative trait loci affecting growth in high growth (hg) mice.Semantic proximity Read ↗

Evolutionary trade-offs between growth and reproduction under obesogenic conditions: sex-biased skeletal and gonadal maturation in miceSemantic proximity Read ↗

Infertility in a line of mice with the high growth mutation is due to luteal insufficiency resulting from disruption at the hypothalamic-pituitary axis.Semantic proximity Read ↗

Consequences of growth hormone (GH) overexpression and GH resistance.Semantic proximity Read ↗

Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.