Article
Genes required for Drosophila nervous system development identified by RNA interference.
Proceedings of the National Academy of Sciences of the United States of America - 16 Nov 2004
Ivanov Andrej I, Rovescalli Alessandra C, Pozzi Paola, Yoo Siuk, Mozer Brian, Li Hsi-Ping, Yu Shu-Hua, Higashida Haruhiro, Guo Vicky, Spencer Michael, Nirenberg Marshall
Abstract excerpt
RNA interference was used to screen 3,314 Drosophila double-stranded RNAs, corresponding to approximately 25% of Drosophila genes, for genes that affect the development of the embryonic nervous system. RNA-interference-mediated gene silencing in Drosophila embryos resulted in loss-of-function mut...
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