Article
RNA interference screen to identify genes required for Drosophila embryonic nervous system development.
Proceedings of the National Academy of Sciences of the United States of America - 27 Mar 2007
Koizumi Keita, Higashida Haruhiro, Yoo Siuk, Islam Mohamad Saharul, Ivanov Andrej I, Guo Vicky, Pozzi Paola, Yu Shu-Hua, Rovescalli Alessandra C, Tang Derek, Nirenberg Marshall
Abstract excerpt
RNA interference (RNAi) has been shown to be a powerful method to study the function of genes in vivo by silencing endogenous mRNA with double-stranded (ds) RNA. Previously, we performed in vivo RNAi screening and identified 43 Drosophila genes, including 18 novel genes required for the development of the embryonic nervous system. In the present study, 22 additional genes affecting embryonic nervous system...
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