Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effects of the ACE gene insertion/deletion polymorphism on glucose tolerance and insulin secretion in elderly people are modified by birth weight.

The Journal of clinical endocrinology and metabolism - 1 Nov 2004

Kajantie Eero, Rautanen Anna, Kere Juha, Andersson Sture, Ylihärsilä Hilkka, Osmond Clive, Barker David J P, Forsén Tom, Eriksson Johan

Abstract excerpt

The I allele of an insertion/deletion (I/D) polymorphism in the angiotensin-converting enzyme gene (ACE) appears to be protective against the complications of type 2 diabetes. Low birth weight, a marker of an adverse intrauterine environment, is associated with higher rates of type 2 diabetes. We examined whether the ACE I/D polymorphism could explain or modify the association between low birth weight and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth Weight
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose Tolerance Test

Share to Infant, Newborn

Share to Insulin

Share to Insulin Secretion

Share to Peptidyl-Dipeptidase A

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 15531537
DOI: 10.1210/jc.2004-0492

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effects of the ACE gene insertion/deletion polymorphism on glucose tolerance and insulin secretion in elderly people are modified by birth weight.PMID 15531537Read ↗

Polymorphisms in the angiotensin converting enzyme gene and growth in the first year of life.Semantic proximity Read ↗

Angiotensin I-converting enzyme gene polymorphism modulates the consequences of in utero growth retardation on plasma insulin in young adults.Semantic proximity Read ↗

The insertion allele at the angiotensin I-converting enzyme gene locus is associated with insulin resistance.Semantic proximity Read ↗

Relationship between angiotensin-converting enzyme gene insertion or deletion polymorphism and insulin sensitivity in healthy newborns.Semantic proximity Read ↗

Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight.Semantic proximity Read ↗

Type 2 diabetes risk alleles are associated with reduced size at birth.Semantic proximity Read ↗

Correlation of angiotensin converting enzyme activity and the genotypes of the I/D polymorphism in the ACE gene with preterm birth and birth weight.Semantic proximity Read ↗

Association of ACE Gene Insertion/Deletion Polymorphism With Birth Weight, Blood Pressure Levels, and ACE Activity in Healthy ChildrenSemantic proximity Read ↗

Influence of the ACE Gene Insertion/Deletion Polymorphism on Insulin Sensitivity and Impaired Glucose Tolerance in Healthy SubjectsSemantic proximity Read ↗

Adiposity gain during childhood, ACE I/D polymorphisms and metabolic outcomes.Semantic proximity Read ↗

Childhood adiposity, adult adiposity, and the ACE gene insertion/deletion polymorphism: evidence of gene-environment interaction effects on adult blood pressure and hypertension status in adulthood.Semantic proximity Read ↗

New evidence for the fetal insulin hypothesis: fetal angiotensinogen M235T polymorphism is associated with birth weight and elevated fetal total glycated hemoglobin at birth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.