Article
Association between genetic variation in the gene for insulin-like growth factor-I and low birthweight.
Lancet (London, England) - 23 Mar 2002
Vaessen Norbert, Janssen Joop A, Heutink Peter, Hofman Albert, Lamberts Steven W J, Oostra Ben A, Pols Huibert A P, van Duijn Cornelia M
Abstract excerpt
Low birthweight is associated with later risk of type 2 diabetes and related disorders. We aimed to show that a polymorphism in the gene for insulin-like growth factor-I, which has proved to raise risk of type 2 diabetes and myocardial infarction, is associated with low birthweight. We recorded birthweight and obtained DNA for 463 adults. Individuals who did not have the wild-type allele of the polymorphism had a...
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