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Article

The A-1087IL-10 allele is associated with cardiovascular disease in SLE.

Atherosclerosis - 1 Dec 2004

Fei Guo-Zhong, Svenungsson Elisabet, Frostegård Johan, Padyukov Leonid

Abstract excerpt

The risk of cardiovascular disease (CVD) in SLE patients is very high. It is therefore surprising that IL-10 has been discussed both as pathogenic in SLE and as an atheroprotective cytokine. In contrast, TNF is believed to be atherogenic and we recently reported that raised activity in the TNF-system is implicated in SLE-related CVD. Twenty-six (aged 52 +/- 8 years) female patients with SLE and a history of CVD...

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Identifiers

PMID: 15530917
DOI: 10.1016/j.atherosclerosis.2004.07.026

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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