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Article

Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.

Disease markers - 1 Jan 2004

Vasen H F A, Hendriks Y, de Jong A E, van Puijenbroek M, Tops C, Bröcker-Vriends A H J T, Wijnen J Th, Morreau H

Abstract excerpt

Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is a dominantly inherited syndrome characterized by the development of colorectal cancer, endometrial cancer and other cancers and the presence of microsatellite instability (MSI) in tumors. The Bethesda guidelines have been propos...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 15528786
DOI: 10.1155/2004/391039
PMCID: PMC3839268

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15528786-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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