Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population-Based Molecular Detection of Hereditary Nonpolyposis Colorectal Cancer

11 Jun 2000

Abstract excerpt

PURPOSE: Cancer morbidity and mortality can be dramatically reduced by colonoscopic screening of individuals with the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, creating a need to identify HNPCC. We studied how HNPCC identification should be carried out on a large scale in a sensitive and efficient manner. PATIENTS AND METHODS: Colorectal cancer specimens from consecutive newly diagnosed patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer
Share to Multiple and Secondary Primary Cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10829038
DOI: 10.1200/jco.2000.18.11.2193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population-Based Molecular Detection of Hereditary Nonpolyposis Colorectal CancerPMID 10829038Read ↗

Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testing.Semantic proximity Read ↗

Identification in Daily Practice of Patients With Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer): Revised Bethesda Guidelines-Based Approach<i>Versus</i>Molecular ScreeningSemantic proximity Read ↗

Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics.Semantic proximity Read ↗

Molecular screening for hereditary nonpolyposis colorectal cancer: a prospective, population-based study.Semantic proximity Read ↗

Microsatellite instability, immunohistochemistry, and additional PMS2 staining in suspected hereditary nonpolyposis colorectal cancer.Semantic proximity Read ↗

Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases.Semantic proximity Read ↗

Identification of mismatch repair gene mutations in young patients with colorectal cancer and in patients with multiple tumours associated with hereditary non-polyposis colorectal cancerSemantic proximity Read ↗

Optimizing the detection of hereditary non-polyposis colorectal cancer: an update.Semantic proximity Read ↗

Review article: Detection and management of hereditary non-polyposis colorectal cancer (Lynch syndrome).Semantic proximity Read ↗

Population‐based detection of Lynch syndrome in young colorectal cancer patients using microsatellite instability as the initial testSemantic proximity Read ↗

Identification of HNPCC by molecular analysis of colorectal and endometrial tumors.Semantic proximity Read ↗

Revised Bethesda Guidelines for Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome) and Microsatellite InstabilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.