Article
Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing.
The Journal of cell biology - 10 Jun 2002
Gadal Olivier, Strauss Daniela, Petfalski Elisabeth, Gleizes Pierre-Emmanuel, Gas Nicole, Tollervey David, Hurt Ed
Abstract excerpt
Many analyses have examined subnucleolar structures in eukaryotic cells, but the relationship between morphological structures, pre-rRNA processing, and ribosomal particle assembly has remained unclear. Using a visual assay for export of the 60S ribosomal subunit, we isolated a ts-lethal mutation, rix9-1, which causes nucleolar accumulation of an Rpl25p-eGFP reporter construct. The mutation results in a single...
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