Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypermethylation of multiple tumor-related genes associated with DMNT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinoma

1 Mar 2011

Abstract excerpt

This study was designed to determine the significance of DNA methyltransferases (DNMTs) in DNA hypermethylation in esophageal squamous cell carcinoma (ESCC) and to identify DNA methylation markers in serum for the early diagnosis of ESCC. A promoter methylation profile of 12 tumor-related genes was assessed using methylation-specific PCR in ESCC and paired non-tumor tissue samples from 47 patients. Expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Esophageal Cancer Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21150312
DOI: 10.4161/epi.6.3.14182

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypermethylation of multiple tumor-related genes associated with DMNT3b up-regulation served as a biomarker for early diagnosis of esophageal squamous cell carcinomaPMID 21150312Read ↗

The detective, prognostic, and predictive value of DNA methylation in human esophageal squamous cell carcinomaSemantic proximity Read ↗

Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma: Biological and Clinical ImplicationsSemantic proximity Read ↗

Identification of key genes by integrating DNA methylation and next-generation transcriptome sequencing for esophageal squamous cell carcinomaSemantic proximity Read ↗

Aberrant DNA Methylation in Esophageal Squamous Cell Carcinoma and its Clinical Implications in Systemic ChemotherapySemantic proximity Read ↗

Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinomaSemantic proximity Read ↗

Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkersSemantic proximity Read ↗

Genome-wide methylation profiling identified methylated KCNA3 and OTOP2 as promising diagnostic markers for esophageal squamous cell carcinomaSemantic proximity Read ↗

Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Discovery and validation of methylation signatures in circulating cell-free DNA for early detection of esophageal cancer: a case-control studySemantic proximity Read ↗

Identification of a DNA Methylome Profile of Esophageal Squamous Cell Carcinoma and Potential Plasma Epigenetic Biomarkers for Early DiagnosisSemantic proximity Read ↗

Targeted bisulfite sequencing identified a panel of DNA methylation-based biomarkers for esophageal squamous cell carcinoma (ESCC)Semantic proximity Read ↗

Specific DNA methylation markers in the diagnosis and prognosis of esophageal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.