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Article

Mitotic regulation of protein 4.1R involves phosphorylation by cdc2 kinase.

Molecular biology of the cell - 1 Jan 2005

Huang Shu-Ching, Liu Eva S, Chan Siu-Hong, Munagala Indira D, Cho Heidi T, Jagadeeswaran Ramasamy, Benz Edward J

Abstract excerpt

The nonerythrocyte isoform of the cytoskeletal protein 4.1R (4.1R) is associated with morphologically dynamic structures during cell division and has been implicated in mitotic spindle function. In this study, we define important 4.1R isoforms expressed in interphase and mitotic cells by RT-PCR and mini-cDNA library construction. Moreover, we show that 4.1R is phosphorylated by p34cdc2 kinase on residues Thr60...

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Identifiers

PMID: 15525677
DOI: 10.1091/mbc.e04-05-0426
PMCID: PMC539157

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Source receipt: pubmed, retrieved 7 Sept 2026.

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