Article
Two distinct domains of protein 4.1 critical for assembly of functional nuclei in vitro.
The Journal of biological chemistry - 15 Nov 2002
Krauss Sharon Wald, Heald Rebecca, Lee Gloria, Nunomura Wataru, Gimm J Aura, Mohandas Narla, Chasis Joel Anne
Abstract excerpt
Protein 4.1R, a multifunctional structural protein, acts as an adaptor in mature red cell membrane skeletons linking spectrin-actin complexes to plasma membrane-associated proteins. In nucleated cells protein 4.1 is not associated exclusively with plasma membrane but is also detected at several important subcellular locations crucial for cell division. To identify 4.1 domains having critical functions in nuclear...
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