Article
Identification of the homozygous recessive genotype for the deficiency of uridine monophosphate synthase in 35-day bovine embryos.
Journal of reproduction and fertility - 1 Jan 1992
Shanks R D, Popp R G, McCoy G C, Nelson D R, Robinson J L
Abstract excerpt
Holstein-Friesian cattle heterozygous for the deficiency of uridine monophosphate (UMP) synthase have half-normal activity of UMP synthase. The homozygous recessive genotype would result in little or no activity, has not been observed among live animals and apparently leads to embryonic mortality...
Topics
- Animals
- Cattle
- Embryo, Mammalian
- Female
- Fetal Death
- Genes, Recessive
- Genotype
- Homozygote
- Multienzyme Complexes
- Orotate Phosphoribosyltransferase
- Orotidine-5'-Phosphate Decarboxylase
- Pregnancy