Article
Real-time PCR for prenatal and preimplantation genetic diagnosis of monogenic diseases.
Molecular aspects of medicine - 1 Jan 2000
Traeger-Synodinos Joanne
Abstract excerpt
The provision of prenatal diagnosis requires the highest standards in laboratory practice to ensure an accurate result. In preimplantation genetic diagnosis protocols additionally have to address the need to achieve an accurate result from 1 to 2 cells within a limited time. Emerging protocols of "non-invasive" prenatal diagnosis, which are based on analysis of free fetal DNA in the circulation of the pregnant...
Topics
- DNA Mutational Analysis
- Female
- Genetic Testing
- Genotype
- Guidelines as Topic
- Humans
- Mutation
- Polymerase Chain Reaction
- Pregnancy
- Preimplantation Diagnosis
- Prenatal Care
- Prenatal Diagnosis