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Article

Role of a KCNH2 polymorphism (R1047 L) in dofetilide-induced Torsades de Pointes.

Journal of molecular and cellular cardiology - 1 Nov 2004

Sun Zhuoqian, Milos Patrice M, Thompson John F, Lloyd David B, Mank-Seymour Amy, Richmond Jodi, Cordes Jason S, Zhou Jun

Abstract excerpt

Various drugs are reported to prolong the QT-interval on the surface ECG, thereby increasing the risk of developing a potentially fatal arrhythmia known as Torsades de Pointes (TdP). TdP case reports for these drugs have often been associated with risk factors such as overdosing, concomitant drug...

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Source

Identifiers

PMID: 15522280
DOI: 10.1016/j.yjmcc.2004.09.001

Genes

KCNH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15522280-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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