Article
A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization.
Cardiovascular research - 1 Jul 2003
Bezzina Connie R, Verkerk Arie O, Busjahn Andreas, Jeron Andreas, Erdmann Jeanette, Koopmann Tamara T, Bhuiyan Zahurul A, Wilders Ronald, Mannens Marcel M A M, Tan Hanno L, Luft Friedrich C, Schunkert Heribert, Wilde Arthur A M
Abstract excerpt
OBJECTIVE: Genetic variants of cardiac ion channels may influence cardiac repolarization. Thereby such variants may modulate the penetrance of primary electrical disorders, contribute to differences in susceptibility to drug-induced QT-prolongation between individuals, or contribute to rhythm dis...
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