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Article

Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation.

BMC biology - 2 Nov 2004

Kaiser Christina, James Stephen R

Abstract excerpt

BACKGROUND: Insulin receptor substrate (IRS) proteins are key moderators of insulin action. Their specific regulation determines downstream protein-protein interactions and confers specificity on growth factor signalling. Regulatory mechanisms that have been identified include phosphorylation of IRS proteins on tyrosine and serine residues and ubiquitination of lysine residues. This study investigated other...

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Share to Protein Processing, Post-Translational
Share to Acetylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Insulin Receptor Substrate Proteins

Share to Mice, Inbred BALB C

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Source

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Identifiers

PMID: 15522123
DOI: 10.1186/1741-7007-2-23
PMCID: PMC529456

Genes

HDAC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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