Article
Auditory-conditioned-fear-dependent c-Fos expression is altered in the emotion-related brain structures of Fyn-deficient mice.
Brain research. Molecular brain research - 4 Nov 2004
Kubota Osamu, Hattori Kotaro, Hashimoto Kenji, Yagi Takeshi, Sato Toshio, Iyo Masaomi, Yuasa Shigeki
Abstract excerpt
Fyn-tyrosine-kinase-deficient mice exhibit increased fearfulness. To elucidate the neural mechanisms of their emotional defects, we compared fyn(-/-) and fyn(+/-) mice by behavioral analysis of conditioned fear and by functional neuroanatomical analysis of the distribution of highly responsive ne...
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