Article
Fragile X mice develop sensory hyperreactivity to auditory stimuli.
Neuroscience - 1 Jan 2001
Chen L, Toth M
Abstract excerpt
Fragile X syndrome is the most prevalent cause of mental retardation. It is usually caused by the transcriptional inactivation of the FMR-1 gene. Although the cognitive defect is the most recognized symptom of fragile X syndrome, patients also show behavioral problems such as hyperarousal, hyperactivity, autism, aggression, anxiety and increased sensitivity to sensory stimuli. Here we investigated whether fragile...
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