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Article

Flow cytometry-based approach to ABCG2 function suggests that the transporter differentially handles the influx and efflux of drugs.

Cytometry. Part A : the journal of the International Society for Analytical Cytology - 1 Dec 2004

García-Escarp Marta, Martínez-Muñoz Vanessa, Sales-Pardo Irene, Barquinero Jordi, Domingo Joan Carles, Marin Pedro, Petriz Jordi

Abstract excerpt

BACKGROUND: To better characterize the function of the ABCG2 transporter in vitro, we generated three cell lines (MXRA, MXRG, and MXRT) stably expressing ABCG2 after transfection of wild-type ABCG2 and two mutants (R482G and R482T), respectively. METHODS: ABCG2 expression and function were analyz...

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Source

Identifiers

PMID: 15517563
DOI: 10.1002/cyto.a.20072

Genes

ABCG2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15517563-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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