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Article

Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells.

The American journal of pathology - 1 Nov 2004

Lu Xiaojun, Arbiser Jack L, West James, Hoedt-Miller Marloes, Sheridan Alison, Govindarajan Baskaran, Harral Julie Wright, Rodman David M, Fouty Brian

Abstract excerpt

During the transformation from a normal to a malignant cell, several mutations are required to bypass the pathways responsible for controlling proliferation. Premalignant cells have acquired some, but not all of these mutations and consequently have not yet attained a malignant phenotype characterized by tumor formation in vivo. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can induce apoptosis...

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Identifiers

PMID: 15509531
DOI: 10.1016/S0002-9440(10)63418-9
PMCID: PMC1618658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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