Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins.

International journal of cancer - 5 Jan 1998

Magal S S, Jackman A, Pei X F, Schlegel R, Sherman L

Abstract excerpt

Induction of apoptosis is a function of external stimuli and cellular gene expression. Many cells respond to DNA damage by the induction of apoptosis, which depends on a functional p53 protein and is signaled by elevation of p53 levels. We have investigated the response of immortalized human kera...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Cycle
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, p53

Share to Mutation

Share to Repressor Proteins

Share to Tumor Cells, Cultured

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 9426696
DOI: 10.1002/(sici)1097-0215(19980105)75:1<96::aid-ijc15>3.0.co;2-b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9426696-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins.PMID 9426696Read ↗

Apoptosis in human papillomavirus16 E7-, but not E6-immortalized human uroepithelial cells.Semantic proximity Read ↗

The E7 protein of human papillomavirus type 16 sensitizes primary human keratinocytes to apoptosisSemantic proximity Read ↗

Cellular responses of HPV-positive cancer cells to genotoxic anti-cancer agents: Repression ofE6/E7-oncogene expression and induction of apoptosisSemantic proximity Read ↗

Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7.Semantic proximity Read ↗

Proliferation-dependent induction of apoptosis by the retinoid CD437 in p53-mutated keratinocytes.Semantic proximity Read ↗

Expression of the human papillomavirus type 16 E7 oncoprotein induces an autophagy-related process and sensitizes normal human keratinocytes to cell death in response to growth factor deprivationSemantic proximity Read ↗

The role of human papillomavirus oncoproteins E6 and E7 in apoptosisSemantic proximity Read ↗

Anticancer Drugs Aimed at E6 and E7 Activity in HPV-Positive Cervical CancerSemantic proximity Read ↗

Induction of apoptosis by p53 is independent of its oligomeric state and can be abolished by HPV-18 E6 through ubiquitin mediated degradation.Semantic proximity Read ↗

Human papillomavirus oncoproteins and apoptosis (Review)Semantic proximity Read ↗

Specific betapapillomaviruses associated with squamous cell carcinoma of the skin inhibit UVB-induced apoptosis of primary human keratinocytesSemantic proximity Read ↗

Human Papillomavirus Type 16 E6 and E7 Cause Polyploidy in Human Keratinocytes and Up-Regulation of G2-M-Phase ProteinsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.