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Article

Induction of apoptosis in human keratinocytes containing mutated p53 alleles and its inhibition by both the E6 and E7 oncoproteins.

International journal of cancer - 5 Jan 1998

Magal S S, Jackman A, Pei X F, Schlegel R, Sherman L

Abstract excerpt

Induction of apoptosis is a function of external stimuli and cellular gene expression. Many cells respond to DNA damage by the induction of apoptosis, which depends on a functional p53 protein and is signaled by elevation of p53 levels. We have investigated the response of immortalized human keratinocytes (HaCaT) bearing mutated alleles of p53 to genotoxic stress and the effect of human papillomavirus (HPV) 16 E6...

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Source

Identifiers

PMID: 9426696
DOI: 10.1002/(sici)1097-0215(19980105)75:1<96::aid-ijc15>3.0.co;2-b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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