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Article

Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathway

27 Dec 2017

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Share to Advanced biosensing and bioanalysis techniques
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 29335203
DOI: 10.1016/j.ejmech.2017.12.077

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Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathwayPMID 29335203Read ↗

Inhibition of telomerase increases the susceptibility of human malignant glioblastoma cells to cisplatin-induced apoptosisSemantic proximity Read ↗

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Multiple Actions of Telomerase Reverse Transcriptase in Cell Death RegulationSemantic proximity Read ↗

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hTERT-based therapy: A universal anticancer approach (Review)Semantic proximity Read ↗

Down-regulation of human telomerase reverse transcriptase through specific activation of RNAi pathway quickly results in cancer cell growth impairmentSemantic proximity Read ↗

TERT suppresses apoptotis at a premitochondrial step by a mechanism requiring reverse transcriptase activity and 14-3-3 protein-binding ability.Semantic proximity Read ↗

Telomerase inhibition may contribute to accelerated mitochondrial aging induced by anti-retroviral HIV treatmentSemantic proximity Read ↗

hTERT Can Function with Rabbit Telomerase RNA: Regulation of Gene Expression and Attenuation of ApoptosisSemantic proximity Read ↗

A highly selective telomerase inhibitor limiting human cancer cell proliferationSemantic proximity Read ↗

Friend or foe? Telomerase as a pharmacological target in cancer and cardiovascular diseaseSemantic proximity Read ↗

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