Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR.

Antimicrobial agents and chemotherapy - 1 Nov 2004

Marín Mercedes, García de Viedma Darío, Ruíz-Serrano María Jesús, Bouza Emilio

Abstract excerpt

Rapid detection of resistance in Mycobacterium tuberculosis can optimize the efficacy of antituberculous therapy and control the transmission of resistant M. tuberculosis strains. Real-time PCR has minimized the time required to obtain the susceptibility pattern of M. tuberculosis strains, but little effort has been made to adapt this rapid technique to the direct detection of resistance from clinical samples. In...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotics, Antitubercular
Share to Antitubercular Agents

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colony Count, Microbial

Share to Drug Resistance, Multiple, Bacterial

Share to Isoniazid

Share to Rifampin

Share to Sputum

Share to Tuberculosis

Source

Open in PubMed Open full text

Identifiers

PMID: 15504855
DOI: 10.1128/AAC.48.11.4293-4300.2004
PMCID: PMC525444

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR.PMID 15504855Read ↗

New real-time PCR able to detect in a single tube multiple rifampin resistance mutations and high-level isoniazid resistance mutations in Mycobacterium tuberculosis.Semantic proximity Read ↗

Fast test for assessing the susceptibility of Mycobacterium tuberculosis to isoniazid and rifampin by real-time PCR.Semantic proximity Read ↗

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF and INH Resistance of M. tuberculosisSemantic proximity Read ↗

Rapid identification of mycobacteria and rapid detection of drug resistance in Mycobacterium tuberculosis in cultured isolates and in respiratory specimens.Semantic proximity Read ↗

Direct detection in clinical samples of multiple gene mutations causing resistance of Mycobacterium tuberculosis to isoniazid and rifampicin using fluorogenic probes.Semantic proximity Read ↗

Mechanisms of drug resistance in Mycobacterium tuberculosis and current status of rapid molecular diagnostic testing.Semantic proximity Read ↗

Direct Detection of Rifampin-ResistantMycobacterium tuberculosisin Respiratory Specimens by PCR-DNA SequencingSemantic proximity Read ↗

Analytical performance of a multi-target open real-time PCR assay for simultaneous detection of tuberculosis, non-tuberculous mycobacteria, and drug resistance in a high-burden settingSemantic proximity Read ↗

Rapid determination of rifampin resistance in clinical isolates of Mycobacterium tuberculosis by real-time PCR.Semantic proximity Read ↗

Detection of multidrug resistance in Mycobacterium tuberculosis.Semantic proximity Read ↗

Molecular characterization of rifampin- and isoniazid-resistant Mycobacterium tuberculosis strains isolated in Poland.Semantic proximity Read ↗

Rapid detection of isoniazid and rifampin resistance mutations in Mycobacterium tuberculosis complex from cultures or smear-positive sputa by use of molecular beacons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.