Article
Synthesis of adenylated molybdopterin: an essential step for molybdenum insertion.
The Journal of biological chemistry - 31 Dec 2004
Llamas Angel, Mendel Ralf R, Schwarz Günter
Abstract excerpt
The molybdenum cofactor (Moco) is part of the active site of all molybdenum (Mo)-dependent enzymes, except nitrogenase. Moco consists of molybdopterin (MPT), a phosphorylated pyranopterin with an enedithiolate coordinating Mo and it is synthesized by an evolutionary old multistep pathway. The plant protein Cnx1 from Arabidopsis thaliana catalyzes with its two domains (E and G) the terminal step of Moco...
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