Article
Genetic dissection of cyclic pyranopterin monophosphate biosynthesis in plant mitochondria.
The Biochemical journal - 31 Jan 2018
Kruse Inga, Maclean Andrew E, Hill Lionel, Balk Janneke
Abstract excerpt
Mitochondria play a key role in the biosynthesis of two metal cofactors, iron-sulfur (FeS) clusters and molybdenum cofactor (Moco). The two pathways intersect at several points, but a scarcity of mutants has hindered studies to better understand these links. We screened a collection of sirtinol-resistant Arabidopsis thaliana mutants for lines with decreased activities of cytosolic FeS enzymes and Moco enzymes. We...
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