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Article

Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion.

Proceedings of the National Academy of Sciences of the United States of America - 2 Nov 2004

McVey Mitch, Larocque Jeannine R, Adams Melissa D, Sekelsky Jeff J

Abstract excerpt

Bloom syndrome is a rare disorder associated with cancer predisposition and genomic instability and is caused by loss of the RecQ helicase BLM. The Drosophila ortholog of BLM (DmBlm) is required for accurate repair of DNA double-strand gaps by homologous recombination. Repair products from DmBlm...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15501916
DOI: 10.1073/pnas.0406157101
PMCID: PMC524851

Genes

BLM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15501916-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

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Formation of deletions during double-strand break repair in Drosophila DmBlm mutants occurs after strand invasion.PMID 15501916Read ↗

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Blm Helicase Facilitates Rapid Replication of Repetitive DNA Sequences in early <i>Drosophila</i> DevelopmentSemantic proximity Read ↗

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