Article
E1AF, an ets-oncogene family transcription factor.
Cancer letters - 8 Dec 2004
Shindoh Masanobu, Higashino Fumihiro, Kohgo Takao
Abstract excerpt
E1AF is an ets-oncogene family transcription factor. E1AF was shown to upregulate multiple matrix metalloproteinase (MMP) genes and contribute to the malignant phenotype of cancer cells by inducing invasive and metastatic activities. E1AF is upregulated by hepatocyte growth factor (HGF) stimulation, which indicates that E1AF would participate in cell motility by HGF/scatter factor. On the other hand, E1AF...
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