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Article

CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8.

Cell death and differentiation - 1 Jan 2005

Barnhart B C, Pietras E M, Algeciras-Schimnich A, Salmena L, Sayama K, Hakem R, Peter M E

Abstract excerpt

CD95 apoptosis resistance of tumor cells is often acquired through mutations in the death domain (DD) of one of the CD95 alleles. Furthermore, Type I cancer cells are resistant to induction of apoptosis by soluble CD95 ligand (CD95L), which does not induce efficient formation of the death-inducin...

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Source

Identifiers

PMID: 15499374
DOI: 10.1038/sj.cdd.4401509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15499374-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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