Article
No association found between gr/gr deletions and infertility in Brazilian males.
Molecular human reproduction - 1 Apr 2006
Carvalho Cláudia M B, Zuccherato Luciana W, Bastos-Rodrigues Luciana, Santos Fabrício R, Pena Sérgio D J
Abstract excerpt
The Y chromosome carries several spermatogenesis genes distributed in three regions: AZFa, AZFb and AZFc. Microdeletions in these regions have been seen in 10% of sterile males with azoospermia or oligozoospermia, the most frequent of them being characterized by a complete deletion of AZFc region. A partial AZFc deletion named gr/gr has been singled out as a risk factor for spermatogenic failure. However, other...
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