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Article

Y-Chromosome Microdeletions: A Review of Prevalence, Screening, and Clinical Considerations

1 Feb 2021

Abstract excerpt

Deletions within the male-specific region of the Y-chromosome, known as Y-Chromosome Microdeletions (YCMs), are present in as many as 5% and 10% of severe oligospermic and azoospermic men, respectively. These microdeletions are distinguished by which segment of the Y chromosome is absent, identified as AZFa (the most proximal segment), AZFb (middle), and AZFc (distal). The reported prevalence of YCMs within the...

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PMID: 33603438
DOI: 10.2147/tacg.s267421

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