Common genetic variants in platelet surface receptors and its association with ischemic stroke.

doi:10.2217/pgs.16.21

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Article

Common genetic variants in platelet surface receptors and its association with ischemic stroke.

Pharmacogenomics - 1 Jun 2016

Milanowski Lukasz, Pordzik Justyna, Janicki Piotr K, Postula Marek

Abstract excerpt

Ischemic stroke has been named one of the leading causes of death worldwide. Whereas numerous biological mechanisms and molecules were found to be associated with stroke, platelets are particularly contributive to its pathogenesis. Recent data indicate considerable variability in platelet phenotype which accounts for differences in platelet surface receptor function, count and reactivity. These features...

Topics

Brain Ischemia
Genetic Variation
Humans
Integrin alpha2
Integrin beta3
Platelet Glycoprotein GPIb-IX Complex
Platelet Membrane Glycoproteins
Polymorphism, Genetic
Receptors, Purinergic P2Y12
Receptors, Thromboxane A2, Prostaglandin H2
Stroke

Source

Open in PubMed

Identifiers

PMID: 27269246
DOI: 10.2217/pgs.16.21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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