Article
FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts.
Molecular biology of the cell - 1 Jan 2005
Pohl Jürgen, Ring Axel, Korkmaz Umine, Ehehalt Robert, Stremmel Wolfgang
Abstract excerpt
We previously reported that lipid rafts are involved in long-chain fatty acid (LCFA) uptake in 3T3-L1 adipocytes. The present data show that LCFA uptake does not depend on caveolae endocytosis because expression of a dominant negative mutant of dynamin had no effect on uptake of [3H]oleic acid, whereas it effectively prevented endocytosis of cholera toxin. Isolation of detergent-resistant membranes (DRMs) from...
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