Article
N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor.
The Journal of biological chemistry - 24 Dec 2004
Kawamura Kazuhiro, Takano Kazunori, Suetsugu Shiro, Kurisu Shusaku, Yamazaki Daisuke, Miki Hiroaki, Takenawa Tadaomi, Endo Takeshi
Abstract excerpt
During skeletal muscle regeneration caused by injury, muscle satellite cells proliferate and migrate toward the site of muscle injury. This migration is mainly induced by hepatocyte growth factor (HGF) secreted by intact myofibers and also released from injured muscle. However, the intracellular machinery for the satellite cell migration has not been elucidated. To examine the mechanisms of satellite cell...
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